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2,2-Dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yl 4-methylbenzenesulfonate

CAS number:1246999-33-6    molecular formula:C20H33NO8S

overview

compound introduction

产品应用: Boc-NH-PEG3-Tos是一种单分散PEG连接剂,可作为PROTAC连接剂。PROTACs包含两个由连接体连接的不同配体;一个是E3泛素连接酶,另一个是目标蛋白。PROTACs使用细胞内泛素-蛋白酶体系统选择性地降解目标蛋白。 Product Application: Boc-NH-PEG3-Tos is a monodisperse PEG linker, which can act as PROTAC linkers. PROTACs contain two different ligands linked by a linker; one for the E3 ubiquitin ligase and the other for the target protein. PROTACs use the intracellular ubiquitin-proteasome system to selectively degrade the target protein.

Specs

Chinese alias-
English alias5,8,11-Trioxa-2-azatridecanoic acid, 13-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester | 2-[2-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate | MFCD27635161 | 2-[2-[2-[2-(Boc-amino)ethoxy]ethoxy]
CAS number1246999-33-6molecular formulaC20H33NO8S
molecular weight447.54 g/molExact mass≥95%
PSA118.000 Ųlogp1.800

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