Acoziborole (SCYX-7158) 是一种安全有效的抗原虫剂,可用于人类非洲锥虫病 (HAT) 的研究。作用于 T. b. brucei S427 菌株,MIC 值为 0.6 µg/mL。 Acoziborole (SCYX-7158) is an effective, safe and orally active antiprotozoal agent for the research of human african trypanosomiasis (HAT). In the T. b. brucei S427 strain, the MIC value for SCYX-7158 is 0.6 µg/mL.
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Acoziborole
CAS number:1266084-51-8 molecular formula:C17H14BF4NO3
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| Chinese alias | 阿克齐硼罗 | ||
| English alias | Acoziborole | A937430 | SCTX-7158 | Benzamide, N-(1,3-dihydro-1-hydroxy-3,3-dimethyl-2,1-benzoxaborol-6-yl)-4-fluoro-2-(trifluoromethyl)- | AC-36374 | 2IOR2OO3GW | 4-fluoro-N-(1-hydroxy-3,3-dimethyl-1,3-dihydro-benzo[c][1,2]oxaborol-6-yl)-2-trifluoromethy | ||
| CAS number | 1266084-51-8 | molecular formula | C17H14BF4NO3 |
| molecular weight | 367.10 g/mol | Exact mass | ≥99% |
| PSA | 58.600 Ų | logp | - |
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