WIN 54954 is an orally active and broad-spectrum antipicornavirus agent. WIN 54954 is effectiveness against human rhinovirus, echovirus 9 and enterovirus infections. In Vitro WIN 54954 reduces plaque formation of 50 of 52 rhinovirus serotypes (MICs ranges from 0.007 to 2.2 μg/mL). WIN 54954 inhibits 15 commonly isolated enteroviruses, with an EC 80 of 0.06 μg/mL. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo WIN 54954 (2-100 mg/kg; p.o.) protects 50% of the mice from developing paralysis following infection with coxsackievirus A-9 and echovirus-9 at the dose of 2 and 100 mg/kg, respectively . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid
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WIN 54954
CAS number:107355-45-3 molecular formula:C18H20Cl2N2O3
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 107355-45-3 | molecular formula | C18H20Cl2N2O3 |
| molecular weight | 383.27 g/mol | Exact mass | ≥98% |
| PSA | 56.900 Ų | logp | 4.600 |
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