Norwogonin, isolated from Scutellaria baicalensis Georgi, possesses antiviral activity against Enterovirus 71 (EV71) with an IC 50 of 31.83 μg/ml In Vitro Norwogonin (0.4, 2, 10, and 50 μg/mL; 48 hours) inhibits EV71 replication in Vero cells and prevents the cytotoxicity induced by EV71 infection. Norwogonin (50 μg/mL; 48 hours) dramatically decreases viral VP2 protein expression. Norwogonin (50 μg/mL; 48 hours) strongly decreases the expression of EV71 NCR gene at 48 h. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: 31.83 μg/ml (EV71)
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Norwogonin
CAS number:4443-09-8 molecular formula:C15H10O5
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| Chinese alias | 挪威黄芩素 | ||
| English alias | - | ||
| CAS number | 4443-09-8 | molecular formula | C15H10O5 |
| molecular weight | 270.24 g/mol | Exact mass | ≥99% |
| PSA | 87.000 Ų | logp | 2.700 |
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