CAS number：380315-80-0 molecular formula：C20H23N3O2S
Tenovin-1防止MDM2介导的p53的降解，涉及泛素化途径，通过抑制SirT1和SirT2的蛋白脱乙酰活性。An inhibitor of SIRT1 and SIRT2. Tenovin-1 protects against MDM2-mediated p53 degradation, which involves ubiquitination, and acts through inhibition of protein-deacetylating activities of SirT1 and SirT2. An inhibitor of SIRT1 and SIRT2.
| Chinese alias | - | ||
| English alias | Q27166342 | SR-01000946350-1 | CCG-208685 | N-(4-acetamidophenylcarbamothioyl)-4-tert-butylbenzamide | HY-13423 | SW133688-2 | N -[[[4-(Acetylamino)phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)benzamide | NCGC00181351-05 | Z56060122 | BRD-K05977823-001 | ||
| CAS number | 380315-80-0 | molecular formula | C20H23N3O2S |
| molecular weight | 369.48 g/mol | Exact mass | ≥98% |
| PSA | 102.000 Ų | logp | 4.400 |
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