CAS number：1056634-68-4 molecular formula：C23H22N6O2
Momelotinib (CYT387)是一种ATP竞争性JAK1/JAK2抑制剂，IC50为11 nM/18 nM，比作用于JAK3选择性约高10倍左右。An inhibitor of JAK1 and JAK2. Momelotinib (CYT387) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3. An inhibitor of JAK1 and JAK2.
| Chinese alias | - | ||
| English alias | C87 | DB11763 | KBioGR_000794 | N-(cyanomethyl)-4-(2-{[4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)benzamide | NSC800800 | NSC-800800 | 2-hydroxy-2,2-diphenylacetic acid (1-ethyl-1-methyl-3-piperidin-1-iumyl) ester | 1056634-68-4 | NCGC00244257-08 | SMR | ||
| CAS number | 1056634-68-4 | molecular formula | C23H22N6O2 |
| molecular weight | 414.47 g/mol | Exact mass | - |
| PSA | 103.000 Ų | logp | 2.6 |
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