CAS number：700874-71-1 molecular formula：C26H27N5O2
LY2109761是一种新型的，选择性的TGF-β receptor type I/II (TβRI/II)双重抑制剂，Ki分别为38 nM和300 nM，对Smad2的磷酸化产生负面影响。A small molecule inhibitor of the TGF-β receptor type 1/type II kinases. LY2109761 is a novel selective TGF-β receptor type I/II (TβRI/II) dual inhibitor with Ki of 38 nM and 300 nM, respectively; shown to negatively affect the phosphorylation of Smad2. A small molecule inhibitor of the TGF-β receptor type 1/type II kinases.
| Chinese alias | - | ||
| English alias | HMS3674E17 | SB19481 | AKOS022183732 | GTPL8075 | BCP9000868 | LY 2109761 | Q27082613 | .ALPHA.-KETOGLUCONIC ACID | Quinoline, 4-(5,6-dihydro-2-(2-pyridinyl)-4H-pyrrolo(1,2-b)pyrazol-3-yl)-7-(2-(4-morpholinyl)ethoxy)- | NCGC00242598-01 | IHLVSLOZUHKNMQ-UH | ||
| CAS number | 700874-71-1 | molecular formula | C26H27N5O2 |
| molecular weight | 441.52 g/mol | Exact mass | - |
| PSA | 65.300 Ų | logp | 2.800 |
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