LY2228820是p38MAPK抑制剂,对p38αMAPK和p38βMAPK的IC50分别为7 nM和3 nM。A p38 MAP Kinase inhibitor with IC50 of 70nM LY2228820 is a novel and potent inhibitor of p38 MAPK with IC50 of 7 nM in a cell-free assay, does not alter p38 MAPK activation. A p38 MAP Kinase inhibitor with IC50 of 70nM
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LY2228820
CAS number:862507-23-1 molecular formula:C26H37FN6O6S2
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| Chinese alias | - | ||
| English alias | A25222 | ZZ-84 | AB02974 | AC-6140 | 3H-Imidazo(4,5-b)pyridin-2-amine, 5-(2-(1,1-dimethylethyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)-3-(2,2-dimethylpropyl)-, methanesulfonate (1:2) | 5-[2-tert-Butyl-5-(4-fluoro-phenyl)-1H-imidazol-4-yl]-3-(2,2-dimethyl-pr | ||
| CAS number | 862507-23-1 | molecular formula | C26H37FN6O6S2 |
| molecular weight | 612.74 g/mol | Exact mass | ≥98% |
| PSA | 211.000 Ų | logp | - |
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