CAS number：1356962-20-3 molecular formula：C24H25ClN6O
AZD-3463是ALK/IGF1R抑制剂。 AZD-3463 (ALK/IGF1R inhibitor) 是一种ALK/IGF1R 抑制剂，对 ALK 作用的 Ki 值为 0.75 nM。AZD-3463 可诱导神经母细胞瘤细胞凋亡 (apoptosis) 和自噬 (autophagy)。 AZD3463 is a novel orally bioavailable ALK inhibitor with Ki of 0.75 nM, which also inhibits IGF1R with equivalent potency.
| Chinese alias | - | ||
| English alias | BCP07685 | Q27074737 | CI 37550 | DTXSID50717792 | HMS3653G05 | N-(4-(4-Aminopiperidin-1-yl)-2-methoxyphenyl)-5-chloro-4-(1H-indol-3-yl)pyrimidin-2-amine | BDBM192752 | NCGC00351596-09 | N-(4-(4-aminopiperidin-1-yl)-2-methoxyphenyl)-5-chloro-4-(1H-indol-3 | ||
| CAS number | 1356962-20-3 | molecular formula | C24H25ClN6O |
| molecular weight | 448.95 g/mol | Exact mass | - |
| PSA | 92.100 Ų | logp | 4.200 |
No numbering system information yet
No physical and chemical property information yet
No safety information yet
No production method and use information yet
No upstream information yet
No downstream information yet
