compound introduction
Alisertib (MLN8237)是Aurora A选择性抑制剂，IC50为1.2 nM，比对Aurora B的抑制性高200倍。 Alisertib (MLN8237) is a selective Aurora A inhibitor with IC50 of 1.2 nM; has >200-fold higher selectivity for Aurora A than Aurora B.
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Alisertib (MLN8237)
CAS number：1028486-01-2 molecular formula：C27H20ClFN4O4
overview
Specs
| Chinese alias | - | ||
| English alias | Alisertib | MLN8237 | MLN-8237 | UNII-O3FX965V0I | MLN8237 (Alisertib) | FT-0672433 | Alisertib (USAN) | Alisertib; MLN8237 | BCP01823 | 4-((9-Chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[c]pyrimido-[4,5-e]azepin-2-yl)amino)-2-methoxybenzoic acid | 4-((9- | ||
| CAS number | 1028486-01-2 | molecular formula | C27H20ClFN4O4 |
| molecular weight | 518.94 g/mol | Exact mass | - |
| PSA | 106.000 Ų | logp | 5 |
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