CAS number：4079-26-9 molecular formula：C15H11NS
PD146176 (NSC168807) 是一种 15-脂氧合酶 (15-LO) 抑制剂，对兔网织红细胞 15-LO 有抑制作用 (Ki=197 nM, IC50=0.54 μM)。PD146176 通过刺激老年三重转基因小鼠的自噬作用逆转认知障碍、脑淀粉样变性和 tau 病理学。 PD 146176 has been used to study its influence on ex vivo leukotriene B4 (LTB4) and lipoxin A4 (LXA4) secretion in adipose tissue.
| Chinese alias | 6,11-二氢 1 苯并硫代吡喃 4,3-b 吲哚 | 6,11-二氢[1]苯并噻喃基[4,3-b]吲哚 | ||
| English alias | 6,11-Dihydro[1]benzothiopyrano[4,3-b]indole | ||
| CAS number | 4079-26-9 | molecular formula | C15H11NS |
| molecular weight | 237.32 g/mol | Exact mass | - |
| PSA | 41.100 Ų | logp | 3.800 |
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