compound introduction
CZC-25146是代谢稳定性的LRRK2抑制剂，对野生型LRRK2和G2019S LRRK2的IC50分别为4.76 nM和6.87 nM。
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CZC 25146
CAS number：1191911-26-8 molecular formula：C22H25FN6O4S
overview
Specs
| Chinese alias | N-[2-[[5-氟-2-[[2-甲氧基-4-(4-吗啉基)苯基]氨基] -4-嘧啶基]氨基]苯基]甲磺酰胺 | ||
| English alias | - | ||
| CAS number | 1191911-26-8 | molecular formula | C22H25FN6O4S |
| molecular weight | 488.54 g/mol | Exact mass | 10mM in DMSO |
| PSA | 126.000 Ų | logp | 2.700 |
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