应用: GW406108X 是特异性的 Kif15 (Kinesin-12) 抑制剂,IC50 为 0.82 uM。GW406108X 是一种有效的自噬 (autophagy) 抑制剂, ATP 竞争性抑制 ULK1,pIC50 为 6.37 (427 nM)。GW406108X 抑制 ULK1 和自噬,而不影响 mTOR 或 AMPK 活性。
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GW406108X
CAS number:1644443-92-4 molecular formula:C20H11Cl2NO4
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Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 1644443-92-4 | molecular formula | C20H11Cl2NO4 |
| molecular weight | 400.21 g/mol | Exact mass | ≥98% |
| PSA | 79.500 Ų | logp | 4.500 |
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