compound introduction
CA77.1 是一种有效的，具有脑渗透性和口服活性的分子伴侣介导自噬 (CMA) 的 激活剂，表现出良好的药代动力学。CA77.1是 AR7 的衍生物，可以增加溶酶体受体 (LAMP2A) 在溶酶体中的表达。CA77.1 可以改善 PS19 小鼠模型的行为和神经病理特征，可用于阿尔茨海默病的研究。
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CA77.1
CAS number：2412270-22-3 molecular formula：C16H12ClN3O
overview
Specs
| Chinese alias | - | ||
| English alias | 2412270-22-3 | MS-24275 | EX-A7534 | N-(4-(6-Chloroquinoxalin-2-yl)phenyl)acetamide | CA77.1 | s6395 | DTXSID701336851 | N-[4-(6-Chloroquinoxalin-2-yl)phenyl]acetamide | AKOS040759645 | HY-134923 | SCHEMBL21793861 | ||
| CAS number | 2412270-22-3 | molecular formula | C16H12ClN3O |
| molecular weight | 297.74 g/mol | Exact mass | ≥98% |
| PSA | 54.900 Ų | logp | 2.700 |
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