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Bonannione A

CAS number:97126-57-3    molecular formula:

overview

compound introduction

Bonannione A (6-Geranylnaringenin; Mimulone) 是一种异戊二烯类黄酮,一种口服有效的蛋白酪氨酸磷酸酶 1B (PTP1B) 抑制剂,IC50为 14 µM。Bonannione A 触发半胱天冬酶依赖性细胞凋亡。Bonannione A 通过 p53 介导的 AMPK/mTOR 通路诱导自噬。Bonannione A 显示出抗炎、抗自由基和抗癌活性。

Specs

Chinese alias-
English alias-
CAS number97126-57-3molecular formula
molecular weight408.500 g/molExact mass-
PSA87.000 Ųlogp6.200

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