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Latifolin

CAS number:10154-42-4    molecular formula:

overview

compound introduction

(-)-Latifolin 是一种类黄酮,通过靶向PI3K/AKT/mTOR/p70S6K信号传导诱导细胞凋亡。(-)-Latifolin 显着抑制口腔鳞状细胞癌 (OSCC) 的细胞增殖,并通过 FAK/Src 失活有效阻断细胞迁移、侵袭和粘附而产生抗转移活性。(-)-Latifolin 抑制自噬相关蛋白和自噬体形成。(-)-Latifolin 通过使坏死性凋亡调节蛋白 (RIP1、RIP3 和 MLKL) 去磷酸化来抑制坏死性凋亡。(-)-Latifolin 具有抗衰老、抗癌、抗炎和心脏保护活性。

Specs

Chinese alias-
English alias-
CAS number10154-42-4molecular formula
molecular weight286.320 g/molExact mass-
PSA58.900 Ųlogp3.700

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