CAS number：623163-52-0 molecular formula：C14H8NO4Cl
MEK抑制剂II是一种选择性有效的MEK抑制剂，对PKC和PKA几乎没有作用。抑制Raf1和ERK1，但仅在高得多的浓度下。MEK抑制剂II具有细胞渗透性。 MEK Inhibitor II is a selectively potent MEK inhibitor, showing little effect on PKC and PKA. Inhibits Raf1 and ERK1, but only at much higher concentrations. MEK Inhibitor II is cell-permeable.
| Chinese alias | - | ||
| English alias | NCI60_031219 | 1-(3-chloro-1,4-dioxonaphthalen-2-yl)pyrrolidine-2,5-dione | GTPL6007 | NSC686549 | NSC-686549 | MEK Inhibitor II | 1-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)pyrrolidine-2,5-dione | BDBM50375664 | SCHEMBL12618420 | 2-Chloro-3-(N-succ | ||
| CAS number | 623163-52-0 | molecular formula | C14H8NO4Cl |
| molecular weight | 289.7 g/mol | Exact mass | - |
| PSA | 71.500 Ų | logp | 1.300 |
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