1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (14:0 Lyso PE) 是一种具有磷酸乙醇胺头部和豆蔻酰尾部的溶血磷脂。游离胺基可在偶联剂存在下与NHS酯偶联或与羧酸偶联。它也诱导PC12细胞的细胞内钙离子一过性增加。在恶性乳腺癌患者的血清样本中，1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine 水平高于健康对照。 应用 14:0 Lyso PE已用于脂质组学分析。也已用于制备脂质。 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (14:0 Lyso PE) is a lysophospholipid with a phosphoethanolamine head and a myristoyl tail. The free amine group can conjugate with NHS active ester or coupled with carboxylic acid in the presence of a coupling agent. It also induces transient increases in intracellular calcium in PC12 cells. Serum levels of 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine are elevated in patients with malignant breast cancer compared to healthy controls. Application 14:0 Lyso PE has been used for lipidomic profiling. It has also been used for the preparation of lipids.
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1-myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine
CAS number：123060-40-2 molecular formula：C19H40NO7P
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| Chinese alias | 1-十四烷酰基-sn-甘油-3-磷酸乙醇胺 | ||
| English alias | 1-myristoylglycerophosphoethanolamine | 2-azaniumylethyl (2R)-2-hydroxy-3-(tetradecanoyloxy)propyl phosphate | RPXHXZNGZBHSMJ-GOSISDBHSA-N | 1-myristoyl-sn-glycero-3-phosphoethanolamine zwitterion | 2-azaniumylethyl [(2R)-2-hydroxy-3-tetradecanoyloxypropy | ||
| CAS number | 123060-40-2 | molecular formula | C19H40NO7P |
| molecular weight | 425.497 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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1-Myristoyl-2-hydroxy-sn-glycerol-3-phosphate ethanolamine | 1-myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine
