Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description: Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is a cytokine expressed by epithelial cells, including keratinocytes, and is important in allergic inflammation. Subsequent studies have shown that TSLP promotes T helper type 2 (TH2) cell responses associated with immunity to some helminth parasites and the pathogenesis of many inflammatory diseases, including atopic dermatitis and asthma. TSLP can promote TH2 cytokine-associated inflammation by directly promoting the effector functions of CD4+ TH2 cells, basophils and other granulocyte populations while simultaneously limiting the expression of DC-derived proinflammatory cytokines and promoting regulatory T cell responses in peripheral tissues.
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Recombinant Human TSLP Protein
CAS number:unknown molecular formula:
overview
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Specs
| Chinese alias | 重组人TSLP蛋白 | 重组人 TSLP 蛋白 | ||
| English alias | thymic stromal lymphopoietin | TSLP | Thymic stromal lymphopoietin protein TSLP | TSLP protein | TSLP_HUMAN | EC 1.3.5.1 | Ip | Iron-sulfur subunit of complex II | ||
| CAS number | unknown | molecular formula | |
| molecular weight | - | Exact mass | 无载体 |
| PSA | - | logp | - |
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