compound introduction
Bazedoxifene是一种第三代选择性雌激素受体调节剂。 Bazedoxifene (TSE-424) 是一种能透过血脑屏障的，非甾体、选择性的雌激素受体调节剂 (SERM)，对 ERα 和 ERβ 作用的 IC50 值分别为 26 nM 和 99 nM，可用于骨质疏松症的研究。Bazedoxifene 也是一种 IL-6/GP130 蛋白相互作用抑制剂，可用于胰腺癌的研究。
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Bazedoxifene
Dangerous GoodsCAS number：198481-32-2 molecular formula：C30H34N2O3
overview
Specs
| Chinese alias | - | ||
| English alias | 1-((4-(2-Hexahydro-1H-azepin-1-yl)ethoxy)phenyl)methyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol | EX-A5409 | HY-A0031 | AS-78494 | Bazedoxifeno [INN-Spanish] | DB06401 | 1-[[4-[2-(azepan-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methylindol-5-ol | ||
| CAS number | 198481-32-2 | molecular formula | C30H34N2O3 |
| molecular weight | 470.6 g/mol | Exact mass | - |
| PSA | 57.900 Ų | logp | 6.100 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS08
Signal word：
Danger
Hazard Statement：
H360: 可能损害生育力或未出生的孩子
Statement of Preventive Measures：
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P203: 使用前，获取、阅读并遵守所有安全说明。 P318: 如果暴露或担心，请就医。
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MSDS
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