compound introduction
(S,R,S)-AHPC-PEG2-NH2 dihydrochloride (VH032-PEG2-NH2 dihydrochloride) 是一种合成的 E3 连接酶配体-linker 偶联物，包含基于 (S,R,S)-AHPC 的 VHL 配体和 2 个单元 PEG linker。可用于合成 PROTAC 分子。
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VH032-PEG2-NH2 dihydrochloride
CAS number：2341796-76-5 molecular formula：C28H41N5O6S.2HCl
overview
Specs
| Chinese alias | (2S,4R)-1-((S)-2-(2-(2-(2-(2-氨基乙氧基)乙氧基)乙酰氨基)-3,3-二甲基丁酰基)-4-羟基-N-(4-(4-甲基噻唑-5-基)苄基)吡咯烷-2-羧酰胺 | ||
| English alias | VH 032 - linker 12 | (2S,4R)-1-((S)-2-(2-(2-(2-Aminoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide | (S,R,S)-AHPC-PEG2-NH2 dihydrochloride | ||
| CAS number | 2341796-76-5 | molecular formula | C28H41N5O6S.2HCl |
| molecular weight | 648.64 g/mol | Exact mass | ≥95% |
| PSA | - | logp | - |
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