CAS number：2098487-52-4 molecular formula：C20H20N2O7
Thalidomide-O-PEG2-propargyl (E3 ligase Ligand-Linker Conjugates 32) 是一种合成的 E3 连接酶配体-linker 偶联物 (E3 ligase ligand-linker conjugate)，包含基于 Thalidomide 的 cereblon 配体和 2 个单元的 PEG linker，应用于 PROTAC 技术。 Thalidomide-O-PEG2-propargyl (E3 ligase Ligand-Linker Conjugates 32) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology；
| Chinese alias | 2-(2,6-二氧代-3-哌啶基)-4-[2-[2-(2-丙炔-1-基氧基)氧基]乙氧基] -1H-异吲哚-1,3(2H)二酮 | 沙利度胺 4'-醚-PEG2-炔 | 沙利度胺-O-二聚乙二醇-炔 | 沙利度胺-O-PEG2-炔丙基 | ||
| English alias | Thalidomide-linker5 | Thalidomide-O-PEG2-propargyl | E3 ligase Ligand-Linker Conjugates 32 | 2-(2,6-Dioxo-3-piperidinyl)-4-[2-[2-(2-propyn-1-yloxy)oxy]ethoxy]-1H-isoindole-1,3(2H)dione | ||
| CAS number | 2098487-52-4 | molecular formula | C20H20N2O7 |
| molecular weight | 400.38 g/mol | Exact mass | ≥97% |
| PSA | 111.000 Ų | logp | 0.100 |
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