Bis-PEG1-PFP ester是一种不可降解 (non-cleavable) 的含 1 个单元 PEG 的 ADC linker,可用于合成 抗体偶联活性分子 (ADC)。 Bis-PEG1-PFP ester is a PEG derivative with two PFP ester moieties. The PFP ester is amine-reactive, stable compound. PFP esters are less susceptible toward hydrolysis compared to NHS esters. The PEG linker increases the water solubility of compounds in aqueous environments.
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Bis-PEG1-PFP ester
CAS number:1807539-02-1 molecular formula:C18H8F10O5
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Specs
| Chinese alias | 双(全氟苯基) 3,3'-氧基二丙酸酯 | 3-(2-吡啶二硫代)丙酸-C6-甘氨酸-亮氨酸-活性酯 | ||
| English alias | (2,3,4,5,6-pentafluorophenyl) 3-[3-oxo-3-(2,3,4,5,6-pentafluorophenoxy)propoxy]propanoate | ||
| CAS number | 1807539-02-1 | molecular formula | C18H8F10O5 |
| molecular weight | 494.24 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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