NNGH 是一种基质分解素-1 (MMP-3) 抑制剂。 MMP-3 既是直接转录靶蛋白,也是 Wnt/β-catenin 信号通路的必要组成。 基质金属蛋白酶 (MMP) 在肿瘤进展的后期发挥着重要作用。 NNGH is a stromelysin-1 (MMP-3) inhibitor. MMP-3 is both a direct transcriptional target and a necessary contributor of the Wnt/β-catenin signaling pathway. Matrix metalloproteinases (MMPs) play a well-defined role in later stages of tumor progression
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NNGH
CAS number:161314-17-6 molecular formula:C13H20N2O5S
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Specs
| Chinese alias | N-羟基-2-[[[(4-甲氧基苯基)磺酰基](2-甲基丙基)氨基]乙酰胺 | ||
| English alias | N-hydroxy-2-[(4-methoxybenzene)(2-methylpropyl)sulfonamido]acetamide | AKOS040744915 | 9P3H27MP46 | mmp-3 inhibitor ii | 2-((4-Methoxyphenyl)sulfonyl-(2-methylpropyl)amino)-N-oxidanyl-ethanamide | N-hydroxy-N~2~-[(4-methoxyphenyl)sulfonyl]-N~2~-(2-methylp | ||
| CAS number | 161314-17-6 | molecular formula | C13H20N2O5S |
| molecular weight | 316.37 g/mol | Exact mass | ≥98% |
| PSA | 104.000 Ų | logp | 1.200 |
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