SR10067 是一种强效、选择性和脑渗透性 REV-ERB 激动剂。SR10067 对 Rev-Erbβ 和 Rev-Erbα 具有高亲和力, IC50 值分别为 160 nM 和 170 nM。 SR10067 可用于代谢疾病和神经精神疾病的研究。 Product description: SR10067 is a potent, selective and brain penetrant REV-ERB agonist. SR10067 has high affinity for Rev-Erbβ and Rev-Erbα with IC50 values of 160 nM and 170 nM, respectively. SR10067 can be used for the research of metabolic diseases and neuropsychiatric disorders.
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SR 10067
CAS number:1380548-02-6 molecular formula:C31H31NO3
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compound introduction
Specs
| Chinese alias | [3-[[4-(1,1-二甲基乙氧基)苯氧基]甲基] -3,4-二氢-2(1H)-异喹啉基] -1-萘甲酮 | ||
| English alias | [3-[[4-(1,1-Dimethylethoxy)phenoxy]methyl]-3,4-dihydro-2(1H)-isoquinolinyl]-1-naphthalenylmethanone | ||
| CAS number | 1380548-02-6 | molecular formula | C31H31NO3 |
| molecular weight | 465.58 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 38.800 Ų | logp | 6.800 |
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