compound introduction
MMP-9 / MMP-13抑制剂I是基于哌嗪的，细胞可渗透的，高效的MMP-9（IC | 50 | = 900 pM）和MMP-13（IC | 50 | = 900 pM）抑制剂。据报道在更高的浓度下抑制MMP-1和MMP-3（IC | 50 | = 43 nM和23 nM）。还充当MMP-7（IC | 50 | = 930 nM）的抑制剂。 MMP-9/MMP-13 Inhibitor I is a piperazine-based, cell-permeable, and highly potent inhibitor of MMP-9 (IC|50|= 900 pM) and MMP-13 (IC|50|= 900 pM). Reported to inhibit MMP-1 and MMP-3 at much higher concentrations (IC|50|= 43 nM and 23 nM, respectively). Also acts as an inhibitor of MMP-7 (IC|50|= 930 nM).
