compound introduction
依那普利-d5马来酸盐是一种标记的依那普利化合物。依那普利是一种血管紧张素转化酶（ACE）抑制剂，被认为比卡托普利更有效。据报道该化合物通过肝水解转化为活性形式依那普利拉。大鼠研究表明，依那普利下调IL-β，IL-6和NF-κB的表达。此外，大鼠研究表明，依那普利上调VEGF和血红素加氧酶-1的表达。 Enalapril-d5 Maleate Salt is a labeled enalapril compound. Enalapril is a angiotensin-converting enzyme (ACE) inhibitor, suggested to be more potent than captopril . The compound is reported to be converted to the active form, enalaprilat , through hepatic hydrolysis. Rat studies indicate that enalapril downregulates the expression of IL-β, IL-6, and NF-κB. Furthermore, rat studies show that enalapril upregulates the expression of VEGF and heme oxygenase-1.
