硫醚酰胺-PC是可分泌的磷脂酶A2(sPLA2)的可逆抑制剂,可与sPLA2的催化位点和活化剂位点结合。PLA2酶被发现为中国眼镜蛇蛇毒,与催化位点相比,它与酶的激活位点更牢固地结合。研究表明,硫醚酰胺-PCs与两个位点结合的能力可能是由于在不抑制该酶的低浓度化合物作用下发生的磷脂酶活化。 产品包装量单指溶质的量 Thioetheramide-PC is a reversible inhibitor of secretory phospholipase A2 (sPLA2) that binds to both the catalytic site and activator site of sPLA2. The PLA2 enzyme is found Chinese cobra snake venom and it binds more firmly to the activator site of the enzyme in comparison to the catalytic site. Research indicates that Thioetheramide-PCs ability to bind to both sites may be due to the phophoslipase activation that occurs with low concentrations of the compound, which does not inhibit the enzyme.
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Thioetheramide PC
CAS number:116457-99-9 molecular formula:C40H83N2O5PS
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| Chinese alias | 硫醚酰胺PC | ||
| English alias | CTK8E7838 | 2-[[(2S)-2-(hexadecanoylamino)-3-hexadecylsulfanylpropoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium | 2-[[(2S)-2-(hexadecanoylamino)-3-hexadecylsulfanyl-propoxy]-hydroxy-phosphoryl]oxyethyl-trimethyl-ammonium | SR-01000947058-1 | SR-0100094 | ||
| CAS number | 116457-99-9 | molecular formula | C40H83N2O5PS |
| molecular weight | 735.1 g/mol | Exact mass | ≥95%,10mg/ml in etha |
| PSA | 110.000 Ų | logp | 14.100 |
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