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13(R)-HODE

CAS number:10219-69-9    molecular formula:C18H32O3

overview

compound introduction

13(R)-HODE是亚油酸与大豆脂氧合酶温育时产生的13-HODE的对映异构体。培养的牛内皮细胞的上清液和膜中13(R)-HODE的存在已归因于COX代谢。13(R)-HODE是U-46619诱导的血小板聚集的弱抑制剂(IC | 50 | = 2.7 µM)。 13(R)-HODE is an enantiomer of 13-HODE produced when linoleic acid is incubated with soybean lipoxygenase. The existence of 13(R)-HODE in the supernatants and membranes of cultured bovine endothelial cells has been attributed to COX metabolism. 13(R)-HODE is a weak (IC|50|= 2.7 μM) inhibitor of U-46619-induced platelet aggregation.

Specs

Chinese alias-
English aliasDTXSID901017287 | (9Z,11E,13R)-13-hydroxyoctadecadienoic acid | LMFA02000035 | SCHEMBL20721739 | 9,11-Octadecadienoic acid, 13-hydroxy-, (9Z,11E,13R)- | (13R)-hydroxy-(9Z,11E)-octadecadienoic acid | AKOS040756149 | 13(R)-HODE | (13R)-HODE | CHEBI:137495 |
CAS number10219-69-9molecular formulaC18H32O3
molecular weight296.44 g/molExact mass≥98%
PSA57.500 Ųlogp5.300

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