2-花生四烯酰基-1-棕榈酰基-sn-甘油-3-磷酸胆碱是在sn-1和sn-2位置包含棕榈酸和花生四烯酸的磷脂。2-花生四烯酸-1-棕榈酰-sn-甘油-3-磷酸胆碱可以天然存在于生物膜中。在体内，2-花生四烯基-1-棕榈酰基-sn-甘油-3-磷酸胆碱被氧化，其产物参与慢性炎症和血管疾病。2-花生四烯酰基-1-棕榈酰基-sn-甘油-3-磷酸胆碱已用于氧化磷脂信号的研究。分离的人骨髓瘤细胞显示2-花生四烯酰基-1-棕榈酰基-sn-甘油-3-磷酸胆碱水平降低。 2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine is a phospholipid that contains palmitic acid and arachidonic acid at the sn-1 and sn-2 positions. 2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine can be found naturally in biological membranes. In vivo, 2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine is oxidized, and its products are involved in chronic inflammation and vascular disease. 2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine has been utilized in the studies of oxidized phospholipid signaling. Isolated human myeloma cells showed decreased levels of 2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine. product description： Phosphatidylcholine (PC) is one of the major glycerophospholipids of the eukaryotic membranes. PC is zwitterionic. PC is synthesized via two pathways in higher eukaryotes like the triple methylation of phosphatidylethanolamine and the cytidine diphosphate (CDP)-choline pathway. application： 16:0-20:4 PC is suitable for use: in the preparation of auto-oxidised phospholipid for electrospray ionisation mass spectroscopic (ESI-MS) analysis in liposome preparation for the treatment of organoid as antigen in enzyme linked immunosorbent assay (ELISA) for the detection of autoantibodies to phospholipids Biochemical/Physiological Effects： Phosphatidylcholine (PC) is essential for maintaining the structure and functions of the membrane. PC is the substrate for sphingomyelin synthesis. PC is the precursor for various second messenger like phosphatidic acid, lysophosphatidic acid, diacylglycerol. PC is the dominant phospholipid present in cancer and neo-neoplastic tissues. Level of 16:0-20:4 PC is less in multiple myeloma cells than in normal plasma cells.
All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry
2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine (PAPC)
CAS number：35418-58-7 molecular formula：C44H80NO8P
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | PAPC | 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine | 16:0-20:4 PC | PC(16:0/20:4(5Z,8Z,11Z,14Z)) | PC(16:0/20:4) | 1-Palmitoyl-2-Arachidonoyl-sn-glycero-3-PC | ||
| CAS number | 35418-58-7 | molecular formula | C44H80NO8P |
| molecular weight | 782.08 g/mol | Exact mass | ≥95% |
| PSA | - | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
No safety information yet
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 1 shareMSDS
Chloroform solution of 1-palmitoyl-2-arachidyl-sn-glycerol-3-phosphate choline | 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine
