compound introduction
TVB-3166 是一种口服有效，可逆和选择性脂肪酸合成酶 (FASN) 抑制剂，对于 FASN 和细胞棕榈酸酯合成的 IC50 分别为 42 nM 和 81 nM。TVB-3166 诱导细胞凋亡，并抑制体内异种移植肿瘤的生长。
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TVB-3166
CAS number：1533438-83-3 molecular formula：C24H24N4O
overview
Specs
| Chinese alias | 4-(1-(5-(3,4-二甲基-1H-吡唑-5-基)-2,4-二甲基苯甲酰基)氮杂环丁烷-3-基)苄腈 | ||
| English alias | Benzonitrile, 4-[1-[5-(4,5-dimethyl-1H-pyrazol-3-yl)-2,4-dimethylbenzoyl]-3-azetidinyl]- | ||
| CAS number | 1533438-83-3 | molecular formula | C24H24N4O |
| molecular weight | 384.47 g/mol | Exact mass | ≥99% |
| PSA | 72.800 Ų | logp | 4.100 |
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