Azemiglitazone (MSDC-0602) 是一种直接的线粒体丙酮酸载体 (mitochondrial pyruvate carrier, MPC) 抑制剂,可调节小鼠和人类的中央碳代谢。 Application: MSDC 0602, an analogue of thiazolidinediones, exhibits low affinity for binding and activation of peroxisome proliferator-activated receptor γ (PPARγ). Thiazolidinediones are effective insulin-sensitizing drugs for treating various metabolic and inflammatory diseases.
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Azemiglitazone (MSDC-0602)
CAS number:1133819-87-0 molecular formula:C19H17NO5S
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| Chinese alias | 阿泽格列酮 (MSDC-0602) | ||
| English alias | MSDC-0602 | (+/-)-5-(4-(2-(3-METHOXYPHENYL)-2-OXOETHOXY)BENZYL)-1,3-THIAZOLIDINE-2,4-DIONE | N17076 | AKOS027382993 | BDBM50466687 | YAUMOGALQJYOJQ-UHFFFAOYSA-N | UNII-81MXZ6QOBM | AZEMIGLITAZONE [WHO-DD] | SCHEMBL623654 | AS-56058 | EX-A5498 | 1133819-87 | ||
| CAS number | 1133819-87-0 | molecular formula | C19H17NO5S |
| molecular weight | 371.41 g/mol | Exact mass | ≥97% |
| PSA | 107.000 Ų | logp | 3.400 |
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