CAS number：1629677-75-3 molecular formula：C30H42N4O8
KZR-616（Zetomipzomib） 是首创的免疫蛋白酶体 (immunoproteasome) 抑制剂，选择性靶向免疫蛋白酶体亚基 LMP7 (IC50: 39/57 nM=hLMP7/mLMP7) 和 LMP2 (IC50: 131/179 nM=hLMP7/mLMP7)。KZR-616用于多种自身免疫性疾病的潜力。 KZR-616（Zetomipzomib）, a first-in-class inhibitor of the immunoproteasome, selectively targets the LMP7 (IC50: 39/57 nM=hLMP7/mLMP7) and LMP2 (IC50: 131/179 nM=hLMP7/mLMP7) subunits of the immunoproteasome. KZR-616（Zetomipzomib）has the potential for the research of multiple autoimmune diseases.
| Chinese alias | - | ||
| English alias | (2S,3R)-N-((S)-3-(cyclopent-1-en-1-yl)-1-((R)-2-methyloxiran-2-yl)-1-oxopropan-2-yl)-3-hydroxy-3-(4-methoxyphenyl)-2-((S)-2-(2-morpholinoacetamido)propanamido)propanamide | BDBM50526811 | ZETOMIPZOMIB [INN] | D-Erythro-3-pentulose, 4,5-anhydro-1-(1-cyclop | ||
| CAS number | 1629677-75-3 | molecular formula | C30H42N4O8 |
| molecular weight | 586.68 g/mol | Exact mass | - |
| PSA | 159.000 Ų | logp | 0.400 |
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