compound introduction
Ac-SVVVRT-NH2 is a PGC-1α modulator that modulates the activity of the human PGC-1α promoter (114%). Ac-SVVVRT-NH2 increases PGC-1α mRNA (125%) and accumulation of intracellular lipids (128%) in subcutaneous human adipocytes. Ac-SVVVRT-NH2 can be used in the research of diseases which is modulated by PGC-1α In Vitro Ac-SVVVRT-NH2 (Ac-SEQ ID No.2-NH 2 , 0.1 mg/mL, 10 days) increases PGC-1α mRNA (125%) and accumulation of intracellular lipids (128%) in subcutaneous human adipocytes. Ac-SVVVRT-NH2 (0.5 mg/mL, 24 h) modulates the activity of the human PGC-1α promoter (114%) in HepG2 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:PGC-1α
