SPOP-IN-6b dihydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC 50 of 3.58 μM. Appearance:Solid In Vitro:SPOP-IN-6b dihydrochloride shows IC 50 s of 2-10.2 μM for A498, Caki-2, Ketr-3, 769-P, 0S-RC-2, and 786-0 cells. SPOP-IN-6b (0.1-3.0 μM; 10 hours) dihydrochloride can suppress SPOP activity, and then increase suppression cancer substrate protein PTEN In Vivo:SPOP-IN-6b (40-80mg/kg; intraperitoneal injection; daily; for 25 days; nude mice) dihydrochloride can slow down the growth of tumour by suppressing SPOP. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Biological Activity:SPOP-IN-6b dihydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC 50 of 3.58 μM.
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SPOP-IN-6b dihydrochloride
CAS number：unknown molecular formula：C28H34Cl2N6O3
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| Chinese alias | SPOP-IN-6b 二盐酸盐 | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C28H34Cl2N6O3 |
| molecular weight | 573.51 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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