Saccharopine (L-Saccharopine) hydrochloride, a lysine degradation intermediate, is a mitochondrial toxin. Lysine and α-ketoglutarate are converted into Saccharopine hydrochloride by the lysine-ketoglutarate reductase. Saccharopine hydrochloride is then ox Appearance:Oil IC50& Target:Human Endogenous Metabolite In Vitro:Saccharopine accumulation leads to mitochondrial damage and functional loss which is induced by saccharopine dehydrogenase (SDH) mutations of α-aminoadipate semialdehyde synthase (AASS)-1 in C. elegans. MCE has not independently confirmed the accurac In Vivo:Saccharopine accumulation induces mitochondrial damage and progressive postnatal growth retardation in Aass mutant mice. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Biological Activity:Saccharopine (L-Saccharopine) hydrochloride, a lysine degradation intermediate, is a mitochondrial toxin. Lysine and α-ketoglutarate are converted into Saccharopine hydrochloride by the lysine-ketoglutarate reductase. Saccharopine hydrochloride is then ox
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Saccharopine hydrochloride
CAS number：unknown molecular formula：C11H21ClN2O6
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| Chinese alias | 盐酸沙卡罗碱 | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C11H21ClN2O6 |
| molecular weight | 312.75 g/mol | Exact mass | ≥97% |
| PSA | - | logp | - |
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