Kynuramine, an endogenously occurring amine, is a fluorescent substrate and probe of plasma amine oxidase. In Vitro Kynuramine inhibits both presynaptic and postsynaptic α-adrenoceptors in vitro. Kynuramine has been shown to act as a partial agonist on serotonin receptors in dog cerebral arteries. Kynuramine (20 μg/mL) frequently causes a small contraction of the ileum but failed to alter the twitch response to cholinergic stimulation. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo Kynuramine (0.064, 0.32, 1.6 or 8 μg; ICV; single does) may serve a physiological role in the modulation of female sexual behavior. Kynuramine (1.25, 2.5 and 5.0 mg/kg; i.v.; single does) increases heart rate and blood pressure in pithed rats. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Female rats. Dosage: 0.064-8 μg. Administration: Intraventricular administration; single does. Result: Produced facilitation of lordosis behavior. Animal Model: Male rats (about 200g). Dosage: 1.25-5.0 mg/kg. Administration: i.v.; single does. Result: Promoted heart rate and blood pressure. Form:Solid
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Kynuramine dihydrochloride
CAS number：36681-58-0 molecular formula：C9H14Cl2N2O
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| Chinese alias | 犬尿明二盐酸盐 | ||
| English alias | 3-amino-1-(2-aminophenyl)propan-1-one;dihydrochloride | EN300-207293 | Z2037273395 | MS-23380 | 3-amino-1-(2-aminophenyl)propan-1-one dihydrochloride | HY-119395B | 3-amino-1-(2-aminophenyl)propan-1-onedihydrochloride | Kynuramine (dihydrochloride) | ||
| CAS number | 36681-58-0 | molecular formula | C9H14Cl2N2O |
| molecular weight | 237.13 g/mol | Exact mass | ≥99% |
| PSA | 69.100 Ų | logp | - |
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