compound introduction
DNP-PEG4-DBCO 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。DNP-PEG4-DBCO 是一种点击化学试剂。它含有 DBCO 基团，可以和含有 Azide 基团的分子发生环张力 (strain) 促进的炔-叠氮环加成反应 (SPAAC)。 DNP-PEG4-DBCO is a PEG derivative containing a DNP moiety and a DBCO moiety. DNP is involved in biological applications such as participating in ion transport across membranes. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG linkers increase the water solubility of the compound in aqueous media.
