3-Acrylamidophenylboronic Acid (contains varying amounts of Anhydride)

3-丙烯酰胺基苯硼酸(AAPBA)属于硼酸类单体化合物。其中硼酸基团(-B(OH)₂)可与某些分子（如二醇或糖）形成可逆共价键。这种独特性质可用在分子传感器设计上，用来检测和定量特定种类的分析物，如糖和生物分子。酰胺基的亲水性更加适合药物递送应用。也可用作合成砌块合成硼酸类聚合物或共聚物，用于生物医学工程、葡萄糖监测生物传感器。 应用 3-丙烯酰胺基苯硼酸可用于： 作为单体合成甲基丙烯酸-3-丙烯酰胺基苯硼酸共聚物(PMAA-co-AAPBA)，用作生物传感器的超分子受体。AAPBA有助于增强共聚物的水溶性和结合亲和力。此共聚物用于水溶液中的碳水化合物感应。 作为单体制备聚（3-丙烯酰胺基苯硼酸-b-二乙二醇二甲基丙烯酸酯），制造用于胰岛素输送的葡萄糖敏感型纳米粒子。AAPBA与葡萄糖分子中二元醇特异性结合可诱发葡萄糖响应该嵌段共聚物。 作为单体和交联剂合成自愈型复合水凝胶，用于组织工程和药物递送体系。这种凝胶可模拟天然组织特性，提供适合细胞生长的环境。AAPBA与丙烯酰胺发生聚合反应，同时作用于羟丙基瓜儿胶瓜耳的(HPG)顺二醇基团，形成具有良好机械强度和快速自愈性质的水凝胶。 3-Acrylamidophenylboronic acid (AAPBA) is a monomeric compound of boronic acid. The boronic acid group (-B(OH)₂) can form reversible covalent bonds with certain molecules such as diols or sugars. This unique property can be used in the design of molecular sensors to detect and quantify specific types of analytes, such as sugars and biomolecules. The hydrophilicity of the amide group makes it more suitable for drug delivery applications. It can also be used as a synthetic building block to synthesize boronic acid polymers or copolymers for use in biomedical engineering and glucose monitoring biosensors. Application 3-Acrylamidophenylboronic acid can be used: As a monomer to synthesize methacrylic acid-3-acrylamidophenylboronic acid copolymer (PMAA-co-AAPBA), which is used as a supramolecular receptor for biosensors. AAPBA helps to enhance the water solubility and binding affinity of the copolymer. This copolymer is used for carbohydrate sensing in aqueous solution. As a monomer to prepare poly (3-acrylamidophenylboronic acid-b-diethylene glycol dimethacrylate) to make glucose-sensitive nanoparticles for insulin delivery. The specific binding of AAPBA to the diol in the glucose molecule can induce glucose response to the block copolymer. As a monomer and cross-linker to synthesize self-healing composite hydrogels for tissue engineering and drug delivery systems. This gel can mimic the properties of natural tissues and provide an environment suitable for cell growth. AAPBA polymerizes with acrylamide and acts on the (HPG) cis-diol group of hydroxypropyl guar guar to form a hydrogel with good mechanical strength and rapid self-healing properties.

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