compound introduction
MK-2048是HIV 整合酶和INR263K 的抑制剂，IC50分别为2.6 nM 和1.5 nM。 MK-2048 is a potent inhibitor of integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively.
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MK-2048
CAS number：869901-69-9 molecular formula：C21H21ClFN5O4
overview
Specs
| Chinese alias | - | ||
| English alias | (6S)-2-((3-Chloro-4-fluorophenyl)methyl)-8-ethyl-1,2,6,7,8,9-hexahydro-10-hydroxy-N,6-dimethyl-1,9-dioxopyrazino(1',2':1,5)pyrrolo(2,3-d)pyridazine-4-carboxamide | (6S)-2-[(3-chloro-4-fluoro-phenyl)methyl]-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-6,7-dih | ||
| CAS number | 869901-69-9 | molecular formula | C21H21ClFN5O4 |
| molecular weight | 461.87 g/mol | Exact mass | - |
| PSA | 107.000 Ų | logp | 2.300 |
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