CAS number：929016-96-6 molecular formula：C20H30N4O2
Pracinostat (SB939)是一种有效的pan-HDAC抑制剂，IC50为40-140 nM，除了HDAC6例外，对III型同工酶SIRT I没有抑制活性。A non-selective inhibitor of HDAC. Pracinostat (SB939) is a potent pan-HDAC inhibitor with IC50 of 40-140 nM with exception for HDAC6. It has no activity against the class III isoenzyme SIRT I. A non-selective inhibitor of HDAC.
| Chinese alias | - | ||
| English alias | Pracinostat | Pracinostat (SB939) | (2E)-3-(2-BUTYL-1-(2-(DIMETHYLAMINO)ETHYL)-1H-BENZIMIDAZOL-5-YL)-N-HYDROXYPROP-2-ENAMIDE | (E)-3-(2-BUTYL-1-(2-DIETHYLAMINOETHYL)-1H-BENZIMIDAZOL-5-YL)-N-HYDROXY-2-PROPENAMIDE | KAEMPFEROL 3-O-.BETA.-D-(6-E-P-COUMAROYLG | ||
| CAS number | 929016-96-6 | molecular formula | C20H30N4O2 |
| molecular weight | 358.48 g/mol | Exact mass | - |
| PSA | 70.400 Ų | logp | 3.100 |
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