TAK-779 是一种非肽类CCR5和CXCR3 拮抗剂,对CCR5的Ki 值为 1.1 nM,并选择性抑制R5 HIV-1。 TAK-779 is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).
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TAK-779
CAS number:229005-80-5 molecular formula:C33H39ClN2O2
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| Chinese alias | - | ||
| English alias | dimethyl-[[4-[[3-(4-methylphenyl)-8,9-dihydro-7H-benzo[7]annulene-6-carbonyl]amino]phenyl]methyl]-(oxan-4-yl)azanium;chloride | TAK 779; TAK779;Takeda 779;Takeda-779;Takeda779 | F84995 | CID 183789 | SCHEMBL48548 | 2H-PyraN,N-dimethyl-N-(4-(2-(p-tolyl)-6, | ||
| CAS number | 229005-80-5 | molecular formula | C33H39ClN2O2 |
| molecular weight | 531.10 g/mol | Exact mass | ≥98% |
| PSA | 38.300 Ų | logp | - |
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