D-erythro-Sphingosine (Erythrosphingosine) hydrochloride is a specific TRPM3 activator. D-erythro-Sphingosine also induces retinoblastoma protein dephosphorylation In Vitro Extracellular application of D-erythro-Sphingosine (20 μM) induces an increase in [Ca 2+ ] i in TRPM3-transfected HEK293 cells within 20 to 30 s after start of application, whereas nontransfected control cells (NT) shows only very small responses. D-erythro-Sphingosine (10 μM) induces currents through TRPM3. Induction of retinoblastoma protein dephosphorylation by D-erythro-Sphingosine (500 nM; 24 h) precede inhibition of growth and a specific arrest in the G0/G1 phase of the cell cycle. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:TRPM3|Retinoblastoma protein
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D-erythro-Sphingosine hydrochloride
CAS number：2673-72-5 molecular formula：C18H38ClNO2
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| Chinese alias | D-赤型鞘氨醇盐酸盐 | ||
| English alias | - | ||
| CAS number | 2673-72-5 | molecular formula | C18H38ClNO2 |
| molecular weight | 336 g/mol | Exact mass | - |
| PSA | 66.500 Ų | logp | - |
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