β-Amyloid (1-40) (rat)

β-Amyloid (1-40) (rat) is a rat form of the amyloid β-peptide, which accumulates as an insoluble extracellular deposit around neurons, giving rise to the senile plaques associated with Alzheimer's disease (AD). β-Amyloid (1-40) (rat) increases 45 Ca 2+ influx, induces neurodegeneration in the rat hippocampal neurons of the CA1 subfield. β-Amyloid (1-40) (rat) induces apoptosis. β-Amyloid (1-40) (rat) can be used for the research of Alzheimer's disease. In Vitro β-Amyloid (1-40) (rat) (1 μM; 1 h) increases 45 Ca 2+ influx and elevates Ca 2+ in cortical synaptosomes. β-Amyloid (1-40) (rat) (3 nM) induces neurodegeneration in the rat hippocampal neurons of the CA1 subfield and induces apoptosis. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo β-Amyloid (1-40) (rat) (1.7 mg; ICV, for 7 d; swiss and C57BL/6 mice) induces the learning and memory deficits in mice. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Swiss and C57BL/6 miceDosage: 1.7 mg Administration: Intracerebroventrical injection; for 7 days Result: Presented spatial learning and memory impairments. Form:Solid

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