SB-505124 hydrochloride 是一种选择性的 TGF-β Receptor type I receptor (ALK4,ALK5,ALK7) 抑制剂,对 LK4,ALK5 的 IC50 值分别为 129 nM 和 47 nM,对 ALK1,2,3 或 6 无作用。 SB-505124 hydrochloride is a selective inhibitor of TGF-β Receptor type I receptor (ALK4, ALK5, ALK7), with IC50s of 129 nM and 47 nM for ALK4, ALK5, respectively, but it does not inhibit ALK1, 2, 3, or 6.
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SB-505124 hydrochloride
CAS number:356559-13-2 molecular formula:C20H21N3O2HCl
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| Chinese alias | - | ||
| English alias | 2-(5-benzo[1,3]dioxol-5-yl-2-tert-butyl-3h-imidazol-4-yl)-6-methylpyridine hydrochloride | BCP19172 | SCHEMBL140197 | SB-505124 HCl | SB505124 hydrochloride | SB-505124 hydrochloride | 356559-13-2 (HCl) | SB-505124hydrochloride | HY-13521A | TGF- beta RI | ||
| CAS number | 356559-13-2 | molecular formula | C20H21N3O2HCl |
| molecular weight | 371.86 g/mol | Exact mass | - |
| PSA | 60.000 Ų | logp | - |
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