Evofosfamide (TH-302) 是一种缺氧 (hypoxia) 激活前药,缺氧 (N2) 和常氧 (21% O2) 环境下,IC50 分别为 10 μM 和 1000 μM。 Evofosfamide (TH-302) is a hypoxia-activated prodrug with IC50 of 10 μM and 1000 μM in hypoxia (N2) and normoxia (21% O2), respectively.
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TH-302
CAS number:918633-87-1 molecular formula:C9H16Br2N5O4P
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Specs
| Chinese alias | - | ||
| English alias | HAP-302 | SB17116 | (1-METHYL-2-NITRO-1H-IMIDAZOLE-5-YL)METHYL N,N'-BIS(2-BROMOETHYL) DIAMIDOPHOSPHATE | EX-A1740 | UNII-8A9RZ3HN8W | HY-10535 | n,n'-bis(2-bromoethyl)phosphorodiamidic acid (1-methyl-2-nitro-1h-imidazol-5-yl)methyl ester | AC-29025 | TH30 | ||
| CAS number | 918633-87-1 | molecular formula | C9H16Br2N5O4P |
| molecular weight | 449.04 g/mol | Exact mass | - |
| PSA | 114.000 Ų | logp | 0.6 |
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