CAS number：844442-38-2 molecular formula：C16H17Cl2N5O2
AT7519是多种CDK抑制剂，作用于CDK1， 2， 4， 6和9时，IC50为10-210 nM，对CDK3作用效果稍弱，对CDK7几乎没有抑制活性。Phase 2。A novel small molecule effective as a pan-Cdk inhibitor for Cdk1, Cdk2, Cdk3, Cdk4, Cdk5 and Cdk6. AT7519 is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210 nM. It is less potent to CDK3 and little active to CDK7. Phase 2. A novel small molecule effective as a pan-Cdk inhibitor for Cdk1, Cdk2, Cdk3, Cdk4, Cdk5 and Cdk6.
| Chinese alias | - | ||
| English alias | NSC773394 | NSC-773394 | SY009677 | BDBM24654 | CCG-264904 | NSC799338 | NSC-799338 | OVPNQJVDAFNBDN-UHFFFAOYSA-N | 4-(2,6-dichlorobenzamido)-N-(piperidin-4-yl)-pyrazole-3-carboxamide | AKOS037515688 | s1524 | J-523077 | 4-{[(2,6-dichlorophenyl)carbonyl]a | ||
| CAS number | 844442-38-2 | molecular formula | C16H17Cl2N5O2 |
| molecular weight | 382.24 g/mol | Exact mass | - |
| PSA | 98.900 Ų | logp | 2.6 |
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