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Aminopurvalanol A

CAS number:220792-57-4    molecular formula:C19H26ClN7O

overview

compound introduction

Aminopurvalanol A 是一种有效的、选择性的、可渗透细胞的 Cyclins/Cdk 复合物抑制剂。Aminopurvalanol A 优先靶向G2/M 期转变进而抑制癌细胞分化。Aminopurvalanol A 通过抑制生理获能依赖性肌动蛋白聚合而抑制精子受精能力。 Product description: Aminopurvalanol A is a potent, selective, and cell permeable inhibitor of Cyclins/Cdk complexes. Aminopurvalanol A preferentially targets the G2/M-phase transition inhibiting cancer cell differentiation. Aminopurvalanol A causes the inhibition of sperm fertilizing ability via the inhibition of physiological capacitation-dependent actin polymerization.

Specs

Chinese alias-
English alias2-{[6-(3-Amino-5-chloroanilino)-9-(propan-2-yl)-1,9-dihydro-2H-purin-2-ylidene]amino}-3-methylbutan-1-ol | NCGC00025348-01 | CHEBI:38937 | (R)-2-((6-((3-Amino-5-chlorophenyl)amino)-9-isopropyl- | aminopurvalanol A | GTPL5927 | SR-01000597531-1 | VIA79257
CAS number220792-57-4molecular formulaC19H26ClN7O
molecular weight403.91 g/molExact mass-
PSA114.000 Ųlogp3.600

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