Necrostatin 2 racemate (Nec-1s, 7-Cl-O-Nec1, Necrostatin-1 stable, Necrostatin 1S)是Necrostatin-1的一种稳态变体(stable variant),它是一种更为特异的RIPK1抑制剂,没有靶向IDO的效果,对RIPK1的选择性比对其他485种人源激酶高1000倍以上。
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7-Cl-O-Nec1
CAS number:852391-15-2 molecular formula:C13H12ClN3O2
overview
compound introduction
Specs
| Chinese alias | 5-((7-氯-1H-吲哚-3-基)甲基)-3-甲基咪唑烷-2,4-二酮 | ||
| English alias | 5-((7-Chloro-1H-indol-3-yl)methyl)-3-methylimidazolidine-2,4-dione | Necrostatin 2 racemate (Nec-1s) | Necrostatin-1 stable | Necrostatin 1S | ||
| CAS number | 852391-15-2 | molecular formula | C13H12ClN3O2 |
| molecular weight | 277.7 g/mol | Exact mass | - |
| PSA | 65.200 Ų | logp | 1.900 |
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