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7-Cl-O-Nec1

CAS number:852391-15-2    molecular formula:C13H12ClN3O2

overview

compound introduction

Necrostatin 2 racemate (Nec-1s, 7-Cl-O-Nec1, Necrostatin-1 stable, Necrostatin 1S)是Necrostatin-1的一种稳态变体(stable variant),它是一种更为特异的RIPK1抑制剂,没有靶向IDO的效果,对RIPK1的选择性比对其他485种人源激酶高1000倍以上。

Specs

Chinese alias5-((7-氯-1H-吲哚-3-基)甲基)-3-甲基咪唑烷-2,4-二酮
English alias5-((7-Chloro-1H-indol-3-yl)methyl)-3-methylimidazolidine-2,4-dione | Necrostatin 2 racemate (Nec-1s) | Necrostatin-1 stable | Necrostatin 1S
CAS number852391-15-2molecular formulaC13H12ClN3O2
molecular weight277.7 g/molExact mass-
PSA65.200 Ųlogp1.900

numbering system

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physicochemical properties

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Production methods and uses

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