CAS number：1469337-95-8 molecular formula：C15H17ClIN3O3
K-Ras(G12C) inhibitor 12是致癌K-Ras(G12C)的变构抑制剂。 Information K-Ras(G12C) inhibitor 12 K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C) . Targets K-Ras(G12C) In vitro K-Ras(G12C) inhibitor 12 belongs to a series of small molecules, which irreversibly bind to a common oncogenic mutant K-Ras(G12C) and blocks K-Ras(G12C) interactions. Some of them decrease viability and increase apoptosis of G12C-containing cancer cell lines.
| Chinese alias | - | ||
| English alias | 1-[4-[2-[(4-chloro-2-hydroxy-5-iodophenyl)amino]acetyl]-1-piperazinyl]-2-propen-1-one | ||
| CAS number | 1469337-95-8 | molecular formula | C15H17ClIN3O3 |
| molecular weight | 449.67 g/mol | Exact mass | - |
| PSA | 72.900 Ų | logp | 1.819 |
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